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Article

How Structure, Mechanics, and Function of the Vasculature Contribute to Blood Pressure Elevation in Hypertension.

The Canadian journal of cardiology - 1 May 2020

Schiffrin Ernesto L

Abstract excerpt

Large conduit arteries and the microcirculation participate in the mechanisms of elevation of blood pressure (BP). Large vessels play roles predominantly in older subjects, with stiffening progressing after middle age leading to increases in systolic BP found in most humans with aging. Systolic BP elevation and increased pulsatility penetrate deeper into the distal vasculature, leading to microcirculatory injury,...

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Identifiers

PMID: 32389338
DOI: 10.1016/j.cjca.2020.02.003

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