Article

Reconstructing bat antiviral immunity using epithelial organoids

2024-04-10

Abstract excerpt

<h4>Summary</h4> Bats are remarkably resilient to viruses with pandemic potential. To resolve largely unknown molecular mechanisms governing their exceptional antiviral immunity, we established an organoid platform to model the entire respiratory airway and intestinal epithelium of the important viral reservoir species Rousettus aegyptiacus (Egyptian fruit bat). These bat organoids exhibit an unexpected diversit...

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Literature Corpus work: 9920cade-60e5-5160-a742-e291e3bc25bf
DOI: 10.1101/2024.04.05.588241

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