Article

Post-fertilization transcription initiation in an ancestral LTR retrotransposon drives lineage-specific genomic imprinting of <i>ZDBF2</i>

2023-11-02

Abstract excerpt

<h4>ABSTRACT</h4> The imprinted ZDBF2 gene is controlled by oocyte-derived DNA methylation, but its epigenetic regulation is quite different from that of other canonically imprinted genes that are dependent on DNA methylation deposited in the gametes. At the ZDBF2 locus, maternal DNA methylation in the imprinted differentially methylated region (DMR) does not persist after implantation. Instead, a transient tra...

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Literature Corpus work: b6f42abd-6ca7-5ea0-9885-16e0945da175
DOI: 10.1101/2023.10.30.564869

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