Article

Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation

2019-12-13

Abstract excerpt

The maternal-to-zygotic transition (MZT) is underpinned by wide-spread transcriptomic and epigenomic remodeling that facilitates totipotency acquisition. Factors regulating MZT vary across species and differences in timing of developmental transitions and motif enrichment at accessible chromatin between human and mouse embryos suggest a distinct regulatory circuitry. Profiling accessible chromatin in bovine preimp...

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Literature Corpus work: f83eb3ac-96f1-5cc1-b291-24e070b970c2
DOI: 10.1101/2019.12.12.874479

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