Article

Evolution of imprinting via lineage-specific insertion of retroviral promoters

2019-08-05

Abstract excerpt

<h4>Summary</h4> Imprinted genes are expressed from a single parental allele. In mammals, this unusual mode of transcription generally depends on the epigenetic silencing of one allele by DNA methylation (DNAme) established in the germline. While many species-specific imprinted orthologues have been documented in eutherians, the molecular mechanisms underlying the evolutionary switch from biallelic to imprinted e...

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Literature Corpus work: a8636fcc-0c54-5c3f-854a-22ec8684aff1
DOI: 10.1101/723254

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