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Article

BATF promotes group 2 innate lymphoid cell–mediated lung tissue protection during acute respiratory virus infection

14 Jan 2022

Abstract excerpt

Activated group 2 innate lymphoid cells (ILC2s) accumulate and promote inflammatory resolution and tissue repair in host defense against acute respiratory viral infections. However, the heterogeneity of ILC2s in the lung and the mechanisms by which ILC2 cells contribute to tissue repair remain elusive. Using single-cell RNA sequencing, we identify a transcriptionally distinct ILC2 subset that showed enrichment...

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PMID: 35030033
DOI: 10.1126/sciimmunol.abc9934

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