Article

Validation of an antigenic site targeted by monoclonal antibodies against Puumala virus

2023-08-10

Abstract excerpt

<h4>ABSTRACT</h4> Identification of B-cell epitopes facilitates the development of vaccines, therapeutic antibodies and diagnostic tools. Previously, the binding site of the bank vole monoclonal antibody (mAb) 4G2 against Puumala virus (PUUV, an orthohantavirus in the Hantaviridae family of the Bunyavirales order) was predicted using a combination of methods, including pepscan, phage-display, and site-directed...

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Literature Corpus work: b6dab153-386c-5cdf-909d-ae1a65e05b10
DOI: 10.1101/2023.08.10.552746

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