Article

Defining of MAbs-neutralizing sites on the surface glycoproteins Gn and Gc of a hantavirus using vesicular stomatitis virus pseudotypes and site-directed mutagenesis

2018-04-26

Abstract excerpt

<h4>ABSTRACT</h4> Earlier four Monoclonal antibodies (MAbs) against surface glycoproteins Gn and Gc of Puumala virus (PUUV, genus Orthohantavirus , family Hantaviridae , order Bunyavirales ) were generated and for three MAbs with neutralizing capacity the localization of binding epitopes was predicted using pepscan and phage-display techniques. In this work, we produced vesicular stomatitis virus (VSV) particl...

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Literature Corpus work: acb39374-62c1-5b1a-8490-879c17bfce4e
DOI: 10.1101/307975

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