A proteogenomic approach to discover novel lncRNA-derived peptides and their potential clinical utility in hepatocellular carcinoma

Abstract excerpt

Peptides are increasingly recognized for their versatile functions in biological contexts but their clinical relevance and utility remain largely unexplored. Proteogenomic approaches can accelerate peptide discovery in clinical samples by integrating proteomic data with genomics and transcriptomics evidence. However, long noncoding RNA (lncRNA)-derived peptides (lncPeps) remain largely unidentified, resulting in u...

Topics

Open a Topic to create a Post that cites this publication.

• Cancer Immunotherapy and Biomarkers
• Immunotherapy and Immune Responses
• Peptidase Inhibition and Analysis
• RNA and protein synthesis mechanisms
• vaccines and immunoinformatics approaches

Identifiers and source

Literature Corpus work

b6d5eccd-88f7-51ec-9ae1-ae6ebdde27b5

DOI

10.1101/2025.09.30.679478