Proteogenomics analysis of non-coding region encoded peptides in normal tissues and five cancer types

Abstract excerpt

Previous proteogenomics studies have identified peptides encoded by non-coding sequences such as pseudogenes and long non-coding RNAs (lncRNAs) in healthy human tissues as well as in cancers. However, these studies are either limited to analyze only healthy or cancerous tissues, lacking direct comparison between them. In this study, we used an established proteogenomics analysis workflow to analyze proteomics data...

Topics

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• Immunotherapy and Immune Responses
• Monoclonal and Polyclonal Antibodies Research
• Mutation
• Neoplasms
• Peptidase Inhibition and Analysis
• Pseudogenes
• RNA and protein synthesis mechanisms
• vaccines and immunoinformatics approaches

Identifiers and source

Literature Corpus work

7e19b8d3-77b0-5221-8c51-8be32dfab855

DOI

10.1101/2020.04.10.029306