Placental TRPV2 is indispensable for normal fetal development.

Abstract excerpt

<title>Abstract</title> <p>TRPV2 is a calcium-permeable ion channel with a broad expression pattern that contributes to neuronal outgrowth, immune response, and cardiac function. Mice lacking Trpv2 are more susceptible to perinatal lethality, a phenotype that cannot be explained by its previously allocated functions. We recently reported functional TRPV2 expression in mouse trophoblast cells and described tempora...

Topics

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• Birth, Development, and Health
• Bone and Bones
• Cholesterol
• Congenital heart defects research
• Musculoskeletal Diseases
• Phenotype
• Pregnancy and preeclampsia studies
• TRPV Cation Channels

Identifiers and source

Literature Corpus work

b699184b-e5da-5eae-a12d-a03b6c418032

DOI

10.21203/rs.3.rs-4690823/v1