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Article

Role of TRPV4 in skeletal function and its mutant-mediated skeletal disorders.

Current topics in membranes - 1 Jan 2022

Das Rashmita, Goswami Chandan

Abstract excerpt

TRPV4 is a non-selective cation channel that belongs to the TRP super family. This channel can be activated by physiological temperatures and mechanical stimuli. In addition, TRPV4 is modulated by several endogenous mediators including specific lipids, cholesterol and their metabolic products. TRPV4 gene is present in all vertebrates and is widely expressed in tissues originating from ectoderm, endoderm and...

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PMID: 36210150
DOI: 10.1016/bs.ctm.2022.07.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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