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HSP40 overexpression in pacemaker neurons protects against circadian dysfunction in a <i>Drosophila</i> model of Huntington’s Disease

2021-12-28

Abstract excerpt

Circadian disturbances are early features of neurodegenerative diseases, including Huntington’s Disease (HD), affecting the quality of life of patients and caregivers. Emerging evidence suggests that circadian decline feeds-forward to neurodegenerative symptoms, exacerbating them, highlighting a need for restoring circadian health. Therefore, we asked whether any of the known neurotoxic modifiers can suppress circ...

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Literature Corpus work
b6530577-6a52-5d37-be50-3b4df352f10d
DOI
10.1101/2021.12.27.474320
Open publication

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HSP40 overexpression in pacemaker neurons protects against circadian dysfunction in a <i>Drosophila</i> model of Huntington’s DiseaseDOI 10.1101/2021.12.27.474320
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