Back to search

Article

High-Resolution Melting PCR-Based SNP Germline Genotyping of <em>KLK3</em>,<em> JAZF1</em>, and <em>HNF1B</em> in Prostate Cancer and Benign Prostatic Hyperplasia in Nigerian Men - A Pilot Study

2026-07-14

Abstract excerpt

<h4>Background: </h4> /Objectives: Prostate cancer (PCa) and benign prostatic hyperplasia (BPH) are highly prevalent among African men. While single-nucleotide polymorphisms (SNPs) in KLK3, HNF1B, and JAZF1 are established risk markers in Western cohorts, their specific allele frequencies and diagnostic utility remain poorly characterized in African populations. This study evaluated the diagnostic accuracy, sensit...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b623eee4-bac5-5482-93f4-c16efc6b8b2e
DOI
10.20944/preprints202607.0909.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
High-Resolution Melting PCR-Based SNP Germline Genotyping of <em>KLK3</em>,<em> JAZF1</em>, and <em>HNF1B</em> in Prostate Cancer and Benign Prostatic Hyperplasia in Nigerian Men - A Pilot StudyDOI 10.20944/preprints202607.0909.v1
Review of prostate cancer genomic studies in AfricaSemantic proximity
Single Nucleotide Polymorphisms Associated With Prostate Cancer Development in Saudi MalesSemantic proximity
Assessing high-resolution melt curve analysis for accurate detection of gene variants in complex DNA fragments.Semantic proximity
Haplotype and Presence-Absence Variation Analysis Using High-Resolution Melting (HRM) Analysis for Genotyping Genes of Interest.Semantic proximity
High Resolution Melting Analysis for Rapid Detection of PIK3CA Gene Mutations in Bladder Cancer: A Mutated Target for Cancer Therapy.Semantic proximity
Detection of Cancer-Associated Gene Mutations in Urinary Cell-Free DNA among Prostate Cancer Patients in South Africa.Semantic proximity
High-resolution DNA melting analysis in clinical research and diagnostics.Semantic proximity
High-resolution melting analysis of single nucleotide polymorphisms.Semantic proximity
Genotyping by high-resolution melting analysis.Semantic proximity
Enhanced primer selection and synthetic amplicon templates optimize high-resolution melting analysis of single-nucleotide polymorphisms in a large population.Semantic proximity
High-resolution melting analysis as a sensitive prescreening diagnostic tool to detect KRAS , BRAF , PIK3CA , and AKT1 mutations in formalin-fixed, paraffin-embedded tissues.Semantic proximity
Is high resolution melting analysis (HRMA) accurate for detection of human disease-associated mutations? A meta analysis.Semantic proximity
Select a neighboring publication to make it the new centre.