Article
Detection of Cancer-Associated Gene Mutations in Urinary Cell-Free DNA among Prostate Cancer Patients in South Africa.
Genes - 27 Sept 2023
Temilola Dada Oluwaseyi, Wium Martha, Paccez Juliano, Salukazana Azola Samkele, Rotimi Solomon O, Otu Hasan H, Carbone Giuseppina M, Kaestner Lisa, Cacciatore Stefano, Zerbini Luiz Fernando
Abstract excerpt
Prostate cancer (PCa) is the most common cause of cancer death among African men. The presence of tumor-specific variations in cell-free DNA (cfDNA), such as mutations, microsatellite instability, and DNA methylation, has been explored as a source of biomarkers for cancer diagnosis. In this study, we investigated the diagnostic role of cfDNA among South African PCa patients. We performed whole exome sequencing...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.