Article

Bromodomain 4 inhibition leads to <i>MYCN</i> downregulation in Wilms’ tumor cells

2021-01-04

Abstract excerpt

Wilms’ tumor is the most common childhood kidney cancer. Two distinct histological subtypes of Wilms’ tumor have been described: tumors lacking anaplasia (the favorable subtype) and tumors displaying anaplastic features (the unfavorable subtype). Children with favorable disease generally have a very good prognosis, while those with anaplasia are oftentimes refractory to standard treatments and suffer poor outcomes...

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Literature Corpus work: b6136b28-8182-5d2c-84c9-9c46d783de40
DOI: 10.1101/2021.01.04.425208

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