Article

Identification of a novel subtype of astrocytes in HIV-associated pain pathogenesis

2023-04-12

Abstract excerpt

<title>Abstract</title> <p>Pathological pain is a frequent complication in HIV patients, yet the underlying mechanism remains elusive, and effective therapeutic targets have not been identified. Reactive astrocytes are specifically activated in the spinal dorsal horn (SDH) of HIV patients with pathological pain and required for HIV-associated pain development in mouse models. These findings suggest that reactive...

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Literature Corpus work: b60e7181-3b94-5842-bff4-e4694d6c7099
DOI: 10.21203/rs.3.rs-2782598/v1

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