Article

Identification of a conserved RNA structure in the <i>TNFRSF1A</i> 3’UTR: Implications for post-transcriptional regulation

2025-06-19

Abstract excerpt

Tumor necrosis factor receptor superfamily 1A gene ( TNFRSF1A ) encodes the TNFR1 protein, a critical regulator of inflammation implicated in various diseases. Using ScanFold with the Integrative Genomics Viewer (IGV) GUI, we identified novel RNA structural elements within the TNFRSF1A gene. Focusing on the 3’UTR, these structures were characterized using reporter assays and targeted DMS-MaPseq. We identified a...

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Literature Corpus work: b5c4a641-8981-502a-96b7-356339ec9dcb
DOI: 10.1101/2025.06.18.660452

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