Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model.

Journal of visualized experiments : JoVE - 20 Mar 2020

Cheng Robert Y S, Patel Nimit L, Back Timothy, Basudhar Debashree, Somasundaram Veena, Kalen Joseph D, Wink David A, Ridnour Lisa A

Abstract excerpt

Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with limited therapeutic options. When compared to patients with less aggressive breast tumors, the 5-year survival rate of TNBC patients is 77% due to their characteristic drug-resistant phenotype and metastatic burden. Toward this end, murine models have been established aimed at identifying novel therapeutic strategies limiting TNBC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to Lung Neoplasms

Share to Phenotype

Share to Triple Negative Breast Neoplasms

Share to Xenograft Model Antitumor Assays

Source

Open in PubMed Open full text

Identifiers

PMID: 32250353
DOI: 10.3791/60316
PMCID: PMC8459207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model.PMID 32250353Read ↗

Non-Animal Models for Studying the Effects of Chemotherapeutic Drugs on Breast Cancer MetastasisSemantic proximity Read ↗

Current Update of Patient-Derived Xenograft Model for Translational Breast Cancer ResearchSemantic proximity Read ↗

Orthotopic Injection of Breast Cancer Cells into the Mammary Fat Pad of Mice to Study Tumor Growth.Semantic proximity Read ↗

XENOBREAST Trial: A prospective study of xenografts establishment from surgical specimens of patients with triple negative or luminal b breast cancerSemantic proximity Read ↗

Large-scale Characterization of Orthotopic Cell Line–Derived Xenografts Identifies TGFβ Signaling as a Key Regulator of Breast Cancer Morphology and AggressivenessSemantic proximity Read ↗

Construction of an Improved Orthotopic Transplantation Model of Breast Cancer and Study of Tumor Metastasis MechanismsSemantic proximity Read ↗

Modeling breast cancer by grafting patient tumor samples in the avian embryo: an <i>in vivo</i> platform for therapy evaluation coupled to large scale molecular analysesSemantic proximity Read ↗

Patient‐Derived Models of Human Breast Cancer: Protocols for In Vitro and In Vivo Applications in Tumor Biology and Translational MedicineSemantic proximity Read ↗

From Hurdles to Breakthroughs: Building and Validating a PSMA-positive Triple-Negative Breast Cancer Mouse Model for Preclinical Targeted Radionuclide TherapySemantic proximity Read ↗

Modeling Metastatic Breast Cancer in MiceSemantic proximity Read ↗

Preclinical Testing Techniques: Paving the Way to New Oncology Screening ApproachesSemantic proximity Read ↗

Functional and genomic characterisation of a xenograft model system for the study of metastasis in triple-negative breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.