Article

Fine mapping of PTSD GWAS reveals a role for amygdala <i>Foxp2</i> in regulation of fear and threat responses

2026-06-26

Abstract excerpt

Post-traumatic Stress Disorder (PTSD) is a debilitating psychiatric condition caused by severe trauma exposure and characterized by ongoing dysregulation of fear processing, hyperarousal, and amygdala activation, but with limited effective treatments. Recent large-scale genome-wide association studies (GWAS) of PTSD have identified the transcription factor FOXP2 as a highly-significant, top putative risk gene. Bot...

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Literature Corpus work: b595d8f3-a25b-5d02-9b05-d92147676566
DOI: 10.64898/2026.06.22.733764

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