Article
Genome-wide gene-based analysis suggests an association between Neuroligin 1 (NLGN1) and post-traumatic stress disorder.
Translational psychiatry - 24 May 2016
Kilaru V, Iyer S V, Almli L M, Stevens J S, Lori A, Jovanovic T, Ely T D, Bradley B, Binder E B, Koen N, Stein D J, Conneely K N, Wingo A P, Smith A K, Ressler K J
Abstract excerpt
Post-traumatic stress disorder (PTSD) develops in only some people following trauma exposure, but the mechanisms differentially explaining risk versus resilience remain largely unknown. PTSD is heritable but candidate gene studies and genome-wide association studies (GWAS) have identified only a modest number of genes that reliably contribute to PTSD. New gene-based methods may help identify additional genes that...
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