Back to search

Article

Within-host diversity improves phylogenetic and transmission reconstruction of SARS-CoV-2 outbreaks

2022-06-07

Abstract excerpt

Accurate inference of who infected whom in an infectious disease outbreak is critical for the delivery of effective infection prevention and control. The increased resolution of pathogen whole-genome sequencing has significantly improved our ability to infer transmission events. Despite this, transmission inference often remains limited by the lack of genomic variation between the source case and infected contacts...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b56b38e7-d65b-5c50-a4a4-daa4f85e2579
DOI
10.1101/2022.06.07.495142
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Within-host diversity improves phylogenetic and transmission reconstruction of SARS-CoV-2 outbreaksDOI 10.1101/2022.06.07.495142
Patterns of within-host genetic diversity in SARS-CoV-2.Semantic proximity
Temporal dynamics of SARS-CoV-2 mutation accumulation within and across infected hostsSemantic proximity
Temporal dynamics of SARS-CoV-2 mutation accumulation within and across infected hosts.Semantic proximity
Acute SARS-CoV-2 infections harbor limited within-host diversity and transmit via tight transmission bottlenecks.Semantic proximity
SARS-CoV-2 within-host diversity and transmission.Semantic proximity
JUNIPER: Reconstructing Transmission Events from Next-Generation Sequencing Data at ScaleSemantic proximity
Within-host genetic diversity of SARS-CoV-2 in the context of large-scale hospital-associated genomic surveillanceSemantic proximity
JUNIPER: Reconstructing Transmission Events from Next-Generation Sequencing Data at ScaleSemantic proximity
SARS-CoV-2 Genomic Diversity in Households Highlights the Challenges of Sequence-Based Transmission InferenceSemantic proximity
Stability of SARS-CoV-2 phylogeniesSemantic proximity
Intra-host Variation and Evolutionary Dynamics of SARS-CoV-2 Population in COVID-19 PatientsSemantic proximity
Limited genomic reconstruction of SARS-CoV-2 transmission history within local epidemiological clustersSemantic proximity
Select a neighboring publication to make it the new centre.