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Article

SARS-CoV-2 intra-host variation shows evidence of transmission and convergent evolution in a university surveillance cohort.

Microbial genomics - 1 Sept 2026

Cavalli Léa, Taylor Bradford P, Schaeffer Beau, Turcinovic Jacquelyn, Connor John H, Hanage William P

Abstract excerpt

Monitoring and understanding the transmission and evolution of SARS-CoV-2 remains a significant public health priority. Within-host genetic variation provides insight into viral evolution during infection and may help infer transmission events. In this study, we analysed intra-host variation in SARS-CoV-2 genome sequences from Boston University's testing mandate. Focusing on intra-host single nucleotide variants...

Read the complete abstract on PubMed

Topics

SARS-CoV-2
Humans
COVID-19
Evolution, Molecular
Genome, Viral
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Universities

Cohort Studies

Phylogeny

Source

Open in PubMed Open full text

Identifiers

PMID: 42704657
DOI: 10.1099/mgen.0.001784
PMCID: PMC13549476

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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