Article

Mutational signatures in esophageal squamous cell carcinoma from eight countries of varying incidence

2021-05-04

Abstract excerpt

Esophageal squamous cell carcinoma (ESCC) shows a remarkable variation in incidence which is not fully explained by known lifestyle and environmental risk factors. It has been speculated that an unknown exogenous exposure(s) could be responsible. Here we combine the fields of mutational signature analysis with cancer epidemiology to study 552 ESCC genomes from eight countries with varying incidence rates. The muta...

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Literature Corpus work: b567ea98-636b-5219-b1c8-d8fdec82a94c
DOI: 10.1101/2021.04.29.21255920

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