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Mutational signatures efficiently identify different mutational processes underlying cancers with similar somatic mutation spectra.

Mutation research - 1 Dec 2017

Zhou Nan, Yuan Yuan, Long Xin, Wu Chuanfang, Bao Jinku

Abstract excerpt

Compared to analyzing mutations with conventional spectra, deciphering mutational signatures provides much greater resolution of biological processes that generate somatic mutations during cancer development. Previous studies of bladder urothelial cancer (BLCA) and cervical squamous cell carcinoma (CESC) mutational signatures failed to uncover different mutational processes underlying the two cancers, which...

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PMID: 28942182
DOI: 10.1016/j.mrfmmm.2017.07.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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