Article
The potential of molecular markers to improve interventions through the natural history of oesophageal squamous cell carcinoma.
Bioscience reports - 14 Aug 2013
da Costa Nathalia Meireles, Soares Lima Sheila Coelho, de Almeida Simão Tatiana, Ribeiro Pinto Luis Felipe
Abstract excerpt
EC (oesophageal cancer) is one of the ten most frequent and fatal tumours worldwide and ESCC (oesophageal squamous cell carcinoma) accounts for about 80% of the cases. The first symptoms of ESCC arise late during the progression of the disease and, therefore, the diagnosis is usually done in advanced stages. This leads to an inefficient treatment and consequently to a poor prognosis. Thus, a comprehensive...
Topics
- Animals
- Biomarkers, Tumor
- Carcinoma, Squamous Cell
- Early Detection of Cancer
- Esophageal Neoplasms
- Esophageal Squamous Cell Carcinoma
- Humans
- Mutation
- Papillomavirus Infections
- Risk Factors
- Tumor Suppressor Protein p53