Article

Comparison of Microsatellite Instability Detection by Immunohistochemistry and Molecular Techniques in Colorectal and Endometrial Cancer

2021-01-07

Abstract excerpt

DNA mismatch repair deficiency (dMMR) testing is crucial for diagnosing Lynch syndrome and detection of microsatellite unstable (MSI) tumors eligible for immunotherapy.In this study, we compared the diagnostic performance of three molecular MSI assays: polymerase chain reaction (PCR), MSI testing by Idylla TM and next-generation-sequencing (NGS) on 49 tumor samples (28 colorectal and 21 endometrial adenocarcinomas...

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Literature Corpus work: b5505847-28e4-5ab2-a2c6-bb26e132a025
DOI: 10.21203/rs.3.rs-130862/v1

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