Article
Detection of microsatellite instability with Idylla MSI assay in colorectal and endometrial cancer.
Virchows Archiv : an international journal of pathology - 1 Sept 2021
Ukkola Iiris, Nummela Pirjo, Pasanen Annukka, Kero Mia, Lepistö Anna, Kytölä Soili, Bützow Ralf, Ristimäki Ari
Abstract excerpt
Universal testing of microsatellite instability (MSI) is recommended for colorectal cancer (CRC) and endometrial cancer (EC) to screen for Lynch syndrome and to aid in assessing prognosis and optimal treatment. We compared the performance of Idylla MSI test to immunohistochemistry (IHC) of mismatch repair (MMR) proteins in consecutive series of 100 CRC and 108 EC samples, as well as in retrospective series of 28...
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