Article

Inherited defects in natural killer cells shape tumor immune microenvironment, clinical outcome and immunotherapy response

2018-11-16

Abstract excerpt

Tumor immune microenvironment (TIME) plays an important role in metastasis and immunotherapy. However, it has been not much known how to classify TIMEs and how TIMEs are genetically regulated. Here we showed that tumors were classified into TIME-rich, -intermediate and -poor subtypes which had significant differences in clinical outcomes, abundances of tumor-infiltrating lymphocytes (TILs), the degree of key immun...

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Literature Corpus work: b4f90cc1-a8af-55a2-9aa9-53dc29c2cf76
DOI: 10.1101/471912

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