Article
Cancer-Cell-Intrinsic Mechanisms Shaping the Tumor Immune Landscape.
Immunity - 20 Mar 2018
Wellenstein Max D, de Visser Karin E
Abstract excerpt
Owing to their tremendous diversity and plasticity, immune cells exert multifaceted functions in tumor-bearing hosts, ranging from anti-tumor to pro-tumor activities. Tumor immune landscapes differ greatly between and within cancer types. Emerging evidence suggests that genetic aberrations in cancer cells dictate the immune contexture of tumors. Here, we review the current understanding of the mechanisms whereby...
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