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Cancer-Cell-Intrinsic Mechanisms Shaping the Tumor Immune Landscape.

Immunity - 20 Mar 2018

Wellenstein Max D, de Visser Karin E

Abstract excerpt

Owing to their tremendous diversity and plasticity, immune cells exert multifaceted functions in tumor-bearing hosts, ranging from anti-tumor to pro-tumor activities. Tumor immune landscapes differ greatly between and within cancer types. Emerging evidence suggests that genetic aberrations in cancer cells dictate the immune contexture of tumors. Here, we review the current understanding of the mechanisms whereby...

Topics

Animals
Biomarkers
Cell Transformation, Neoplastic
Disease Susceptibility
Gene Expression Regulation, Neoplastic
Genetic Association Studies
Genetic Predisposition to Disease
Humans
Immune System
Immunomodulation
Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Signal Transduction

Tumor Microenvironment

Source

Identifiers

PMID: 29562192
DOI: 10.1016/j.immuni.2018.03.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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