Article

FOG2 coding variant Ser657Gly is associated with Coronary Microvascular Disease through altered hypoxia-mediated gene transcription

2023-05-28

Abstract excerpt

<h4>Rationale</h4> The coronary microvasculature is crucial for proper cardiac function, and coronary microvascular disease (CMVD) has emerged as an underdiagnosed and undertreated cause of ischemic heart disease. Friend of GATA 2 (FOG2) is a transcriptional co-regulator crucial for coronary development and the maintenance of the coronary microvasculature in adult mice.Little is known about the role of FOG2 in hum...

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Literature Corpus work: b479efb5-dbd7-5c44-90ad-80911f18312d
DOI: 10.1101/2023.05.22.23290352

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