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Article

GATA2 is associated with familial early-onset coronary artery disease.

PLoS genetics - 25 Aug 2006

Connelly Jessica J, Wang Tianyuan, Cox Julie E, Haynes Carol, Wang Liyong, Shah Svati H, Crosslin David R, Hale A Brent, Nelson Sarah, Crossman David C, Granger Christopher B, Haines Jonathan L, Jones Christopher J H, Vance Jeffery M, Goldschmidt-Clermont Pascal J, Kraus William E, Hauser Elizabeth R, Gregory Simon G

Abstract excerpt

The transcription factor GATA2 plays an essential role in the establishment and maintenance of adult hematopoiesis. It is expressed in hematopoietic stem cells, as well as the cells that make up the aortic vasculature, namely aortic endothelial cells and smooth muscle cells. We have shown that GA...

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Source

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Identifiers

PMID: 16934006
DOI: 10.1371/journal.pgen.0020139
PMCID: PMC1557786

Genes

GATA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16934006-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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