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Article

Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart.

The Journal of clinical investigation - 1 Jun 2009

Zhou Bin, Ma Qing, Kong Sek Won, Hu Yongwu, Campbell Patrick H, McGowan Francis X, Ackerman Kate G, Wu Bingruo, Zhou Bin, Tevosian Sergei G, Pu William T

Abstract excerpt

Aberrant transcriptional regulation contributes to the pathogenesis of both congenital and adult forms of heart disease. While the transcriptional regulator friend of Gata 2 (FOG2) is known to be essential for heart morphogenesis and coronary development, its tissue-specific function has not been previously investigated. Additionally, little is known about the role of FOG2 in the adult heart. Here we used...

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Share to Aging
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryo, Mammalian

Share to Gene Expression Regulation, Developmental

Share to Microscopy, Electron

Share to Myocardium

Share to Neovascularization, Physiologic

Source

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Identifiers

PMID: 19411759
DOI: 10.1172/JCI38723
PMCID: PMC2689123

Genes

GATA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart.PMID 19411759Read ↗

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