Article

Somatic mutations in both blood cells and vascular endothelium from patients with severe coronary artery diseases

2022-01-24

Abstract excerpt

<h4>ABSTRACT</h4> Individuals with clonal hematopoiesis of indeterminate potential (CHIP) is associated with a 2-4 fold increase in cardiovascular diseases (CVDs). While most studies focus on mutant blood cells, we propose that a better insight into the CHIP-CVD connection can be obtained by examining the genetic mutations in both the vascular endothelium and peripheral blood samples from the same patient. In this...

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Identifiers and source

Literature Corpus work: 27dc23b5-47cf-5182-9027-b129ca4556de
DOI: 10.1101/2022.01.17.22269173

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