Article

Metabolism regulates muscle stem cell self-renewal by connecting the microenvironment and histone acetylation

2023-07-05

Abstract excerpt

<h4>SUMMARY</h4> Skeletal muscle contains a resident population of somatic stem cells capable of both self-renewal and differentiation. The signals that regulate this important decision have yet to be fully elucidated. Here we use metabolomics and mass spectrometry imaging (MSI) to identity a state of localized hyperglycaemia following skeletal muscle injury. We show that committed muscle progenitor cells exhibit...

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Literature Corpus work: b45d019d-ed42-5607-95e2-7755a437e792
DOI: 10.1101/2023.07.04.547746

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