Article

Skeletal muscle hypertrophy rewires glucose metabolism: an experimental investigation and systematic review

2022-12-08

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Proliferating cancer cells shift their metabolism toward glycolysis even in the presence of oxygen to especially generate glycolytic intermediates as substrates for anabolic reactions. We hypothesize that a similar metabolic remodeling occurs during skeletal muscle hypertrophy. <h4>Methods</h4> We used mass spectrometry in hypertrophying C2C12 myotubes in vitro and plantar...

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Literature Corpus work: a54ed46c-5463-5bbd-8698-281b12c23803
DOI: 10.1101/2022.12.08.519580

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