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Exploring metabolic pathways that contribute to the stem cell phenotype.

Biochimica et biophysica acta - 1 Feb 2013

Vacanti Nathaniel M, Metallo Christian M

Abstract excerpt

BACKGROUND: Stem cells must negotiate their surrounding nutritional and signaling environment and respond accordingly to perform various functions. Metabolic pathways enable these responses, providing energy and biosynthetic precursors for cell proliferation, motility, and other functions. As a result, metabolic enzymes and the molecules which control them are emerging as attractive targets for the manipulation...

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PMID: 22917650
DOI: 10.1016/j.bbagen.2012.08.007

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