Article

Metabolic control of histone acetylation for precise and timely regulation of minor ZGA in early mammalian embryos

2022-06-12

Abstract excerpt

Metabolism feeds into the regulation of epigenetics via metabolic enzymes and metabolites. However, metabolic features, and their impact on epigenetic remodeling during mammalian pre-implantation development, remain poorly understood. In this study, we established the metabolic landscape of mouse pre-implantation embryos from zygote to blastocyst, and quantified some absolute carbohydrate metabolites. We integrate...

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Identifiers and source

Literature Corpus work: f54a1163-0862-5ac9-8320-3cb315abb4c1
DOI: 10.1101/2022.06.10.495405

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