Article

O-GlcNAcylation regulates PPAR-driven metabolic programming in intestinal stem cells

2026-03-16

Abstract excerpt

<h4>SUMMARY</h4> Diet deeply influences health and disease risk by reshaping cellular metabolism. In the intestine, dietary nutrients directly affect intestinal stem cell (ISC) behavior, yet the regulatory mechanisms linking metabolism to transcriptional control remain poorly defined. Because mitochondria function as central metabolic hubs, we focused on mitochondrial signaling to understand how nutrient utilizat...

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Literature Corpus work: 1e2ca8db-9cc6-5574-9d26-b37808d1fb29
DOI: 10.64898/2026.03.13.711696

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