Article
Metabolic reprogramming as a novel regulator of skeletal muscle development and regeneration
12 Feb 2013
Abstract excerpt
Adult skeletal muscle contains a resident population of stem cells, termed satellite cells, that exist in a quiescent state. In response to an activating signal (such as physical trauma), satellite cells enter the cell cycle and undergo multiple rounds of proliferation, followed by differentiation, fusion, and maturation. Over the last 10-15 years, our understanding of the transcriptional regulation of this stem...
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