Article
Digital PCR-based deep quantitative profiling delineates heterogeneity and evolution of uveal melanoma
2024-02-02
Abstract excerpt
Uveal melanoma is an aggressive intraocular tumour characterised by a limited number of genetic alterations. However, the evolution of this malignancy remains enigmatic. In this study, we performed a deep quantitative analysis of 80 primary uveal melanomas by novel digital PCR-based approaches. Mutations were quantified by targeted and drop-off mutation assays, copy number alterations were precisely measured by qu...
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Identifiers and source
- Literature Corpus work
- b45b92ed-4d99-5e26-b69d-90188f308103
- DOI
- 10.1101/2024.01.30.24301871