Article

Extrapolating histone marks across developmental stages, tissues, and species: an enhancer prediction case study

2014-10-25

Abstract excerpt

<h4>Background</h4> Dynamic activation and inactivation of gene regulatory DNA produce the expression changes that drive the differentiation of cellular lineages. Identifying regulatory regions active during developmental transitions is necessary to understand how the genome specifies complex developmental programs and how these processes are disrupted in disease. Gene regulatory dynamics are mediated by many fac...

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Literature Corpus work: b3bffeef-c86a-58da-9679-58d06ca8d519
DOI: 10.1101/010710

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