Article

Systemic interindividual epigenetic variation in humans is associated with transposable elements and under strong genetic control

2022-05-28

Abstract excerpt

Genetic variants can modulate phenotypic outcomes via epigenetic intermediates, for example by affecting DNA methylation at CpG dinucleotides (methylation quantitative trait loci – mQTL). Here, we present the first large-scale assessment of mQTL at human genomic regions selected for interindividual variation in CpG methylation (correlated regions of systemic interindividual variation – CoRSIVs). We used target-cap...

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Literature Corpus work: b31c9c12-e727-5aa6-9789-07db4d372575
DOI: 10.1101/2022.05.27.493722

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