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Article

Genetic regulation of methylation across East Asian and European populations.

Nature communications - 11 Feb 2026

Liu Ruize, Chen Tzu-Ting, Xia Yan, Lin Shu-Chin, Ge Tian, Chen Chia-Yen, Feng Yen-Chen Anne, Huang Hailiang, Lin Yen-Feng

Abstract excerpt

Methylation quantitative trait loci (mQTL) studies have predominantly focused on European populations (EUR), limiting understanding of the genetic regulation of DNA methylation in other populations. We conduct an East Asian (EAS) mQTL analysis, integrating data from three independent samples comprising 7619 Han Chinese individuals. We identified 331,048 mCpGs, including 28,978 novel mCpGs in EAS. While observing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41672998
DOI: 10.1038/s41467-026-69372-6
PMCID: PMC13002944

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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