Article

Abnormal CD8 T cells induce and track Alzheimer’s-like neurodegeneration

2021-02-26

Abstract excerpt

<title>Abstract</title> <p>Sporadic Alzheimer’s disease, the most common neurodegenerative disorder of aging, is characterized by cerebral plaques and neurofibrillary tangles. Experimental rodents develop plaques but neither tangles nor substantial neurodegeneration under conditions that guarantee Alzheimer’s in humans, suggesting rodents lack critical co-initiation factors. Accumulation of antigen-reactive memor...

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Literature Corpus work: b2fcba3f-57d1-543d-a335-ca2eb63eac86
DOI: 10.21203/rs.3.rs-199647/v1

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