Article

Functional Contribution of Cancer-Associated Fibroblasts in Glioblastoma

2022-04-08

Abstract excerpt

The abundance and biological contribution of cancer associated fibroblasts (CAFs) in glioblastoma are poorly understood. Here, we applied single-cell RNA sequencing and spatial transcriptomics analyses to identify and characterize CAFs in human glioblastoma tumors and then performed functional enrichment analysis and in vitro assays to investigate their interactions with malignant glioblastoma cells. We found tha...

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Literature Corpus work: b2efe593-9a53-5ed6-a98d-b49127d57a22
DOI: 10.1101/2022.04.07.487495

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