Article

Spatial distribution and functional relevance of FGFR1 and FGFR2 expression for glioblastoma tumor invasion

2023-01-10

Abstract excerpt

Glioblastoma is the most lethal brain cancer in adults. These incurable tumors are characterized by profound heterogeneity, therapy resistance, and diffuse infiltration. These traits have been linked to cancer stem cells, which are important for glioblastoma tumor progression and recurrence. The fibroblast growth factor receptor 1 (FGFR1) signaling pathway is a known regulator of therapy resistance and cancer stem...

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Literature Corpus work: b070b42c-9350-5606-a06a-81d041074cac
DOI: 10.1101/2023.01.10.523434

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