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Spatial distribution and functional relevance of FGFR1 and FGFR2 expression for glioblastoma tumor invasion

12 Aug 2023

Abstract excerpt

Glioblastoma is the most lethal brain cancer in adults. These incurable tumors are characterized by profound heterogeneity, therapy resistance, and diffuse infiltration. These traits have been linked to cancer stem cells, which are important for glioblastoma tumor progression and recurrence. The fibroblast growth factor receptor 1 (FGFR1) signaling pathway is a known regulator of therapy resistance and cancer...

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PMID: 37579831
DOI: 10.1016/j.canlet.2023.216349

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