Article

DOA/CLK2 phosphorylates Fl(2)d/WTAP to enhance m <sup>6</sup> A mRNA methyltransferase complex activity

2024-11-26

Abstract excerpt

N 6 -methyladenosine (m 6 A) is the most abundant internal modification in messenger RNA (mRNA) providing an essential layer to the control of gene expression important to many biological processes. A megadalton writer complex deposits m 6 A methyl marks that are then read by YTH domain containing proteins. Deposition of m 6 A is thought to be regulated by cellular signalling but how remains uncertain. We ident...

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Literature Corpus work: b2d02066-6b63-541a-a944-9f9d60454c62
DOI: 10.1101/2024.11.25.625202

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