Article
The Drosophila melanogaster DmCK2beta transcription unit encodes for functionally non-redundant protein isoforms.
Gene - 7 Jun 2006
Jauch Eike, Wecklein Heike, Stark Felix, Jauch Mandy, Raabe Thomas
Abstract excerpt
Genes encoding for the two evolutionary highly conserved subunits of a heterotetrameric protein kinase CK2 holoenzyme are present in all examined eukaryotic genomes. Depending on the organism, multiple transcription units encoding for a catalytically active CK2alpha subunit and/or a regulatory CK2beta subunit may exist. The phosphotransferase activity of members of the protein kinase CK2alpha family is thought to...
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